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RO2959 Hydrochloride

CAT: 0013-GTR19167056-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167056-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO2959 Hydrochloride is a selective CRAC channel inhibitor with an IC50 of 402 nM and a potent suppressor of human IL-2 production. This compound is a valuable research tool for studying T-cell activation and calcium signaling in both cellular and animal models of immune dysfunction.
CAS Number
1219927-22-6
Product Name Alternative
CRAC Channel, CRAC channel, CalciumChannel, Calcium Channel, Calcium release-activated channels, Ca2+ release-activated Ca2+ channels, anti-proliferation, failure, heart, Inhibitor, Interleukin Related, Interleukin, IL Receptor, Orai1, inhibit, ILReceptor, IL-2, IP3, RO 2959, RO 2959 Hydrochloride, RO2959, RO-2959, RO2959 HCl, RO2959 Hydrochloride, RO-2959 Hydrochloride, SOCE, Stim1, T-cell
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
97.42% (May vary between batches)
Solubility
DMSO:10 mg/mL (21.55 mM)
Smiles
Cl.Cc1cnc (s1) N1CCC (C) =C (C1) c1cnc (NC (=O) c2c (F) cccc2F) cn1
Molecular Formula
C21H20ClF2N5OS
Molecular Weight
463.93
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
T8867-01RO2959 Hydrochloride
HY-113618A-01RO2959 (hydrochloride)
A22085-25RO2959 hydrochloride 25mg
A22085-1RO2959 hydrochloride 1mg
A22085-100RO2959 hydrochloride 100mg
A22085-50RO2959 hydrochloride 50mg
A22085-10RO2959 hydrochloride 10mg
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A22085-10mM-DRO2959 hydrochloride 10mM * 1mL in DMSO
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