Products for Research Use Only

Bractoppin

CAT: 0013-GTR19167050-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167050-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bractoppin is a potent and selective small-molecule inhibitor of the human BRCA1 tBRCT domain, disrupting phosphopeptide binding with nanomolar IC50. Its unique engagement of a hydrophobic pocket confers selectivity, making it a valuable chemical probe for studying BRCA1 function in DNA damage repair pathways in cellular and biochemical assays.
CAS Number
2290527-07-8
Product Name Alternative
Bractoppin, BRCA1 tBRCT, DNA break, DNA damage, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, G2 arrest, Inhibitor, inhibit, RNASynthesis, RNA Synthesis, RAD51, phosphopeptide
Field of Research
Cell Biology, Molecular Biology
Purity
98.38% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.96 mM) ; DMSO:83.3 mg/mL (200.98 mM)
Smiles
Fc1ccccc1CN1CCN (CC1) C (=O) c1ccc2[nH]c (nc2c1) -c1ccccc1
Molecular Formula
C25H23FN4O
Molecular Weight
414.47
Storage Conditions
-20°C
Notes
For research use only.