Products for Research Use Only

1-Methylguanosine

CAT: 0013-GTR19166496-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166496-01Size:1 mg
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Description
1-Methylguanosine is a modified nucleoside resulting from RNA methylation and degradation. Elevated urinary levels of this molecule have been associated with certain cancers, making it a potential biomarker for oncology research in both in vitro and in vivo studies.
CAS Number
2140-65-0
Product Name Alternative
1 Methylguanosine, 1Methylguanosine, 1-Methylguanosine, Endogenous Metabolite, EndogenousMetabolite, Human Endogenous Metabolite, N1-Methylguanosine
Field of Research
Metabolism Research
Purity
98.11% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.46 mM) ; DMSO:120 mg/mL (403.67 mM)
Smiles
Cn1c (N) nc2n (cnc2c1=O) [C@@H]1O[C@H] (CO) [C@@H] (O) [C@H]1O
Molecular Formula
C11H15N5O5
Molecular Weight
297.27
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-Methylguanosine

1-methylguanosine is guanosine substituted with a methyl group at position N-1. It has a role as a metabolite.

CAS Number2140-65-0
PubChem CID96373
IUPAC Name2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one
Molecular FormulaC11H15N5O5
Molecular Weight297.27
XLogP-1.7
Topological Polar Surface Area146
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Heavy Atom Count21
Formal Charge0
Complexity474
SMILES
CN1C(=O)C2=C(N=C1N)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
InChI
InChI=1S/C11H15N5O5/c1-15-9(20)5-8(14-11(15)12)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14)/t4-,6-,7-,10-/m1/s1
InChIKey
UTAIYTHAJQNQDW-KQYNXXCUSA-N
Chemical Structure
2D Structure
2D structure of 1-Methylguanosine
CAS: 2140-65-0
CID: 96373
Formula: C11H15N5O5
MW: 297.27
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight297.27
XLogP3-1.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass297.10731860
Monoisotopic Mass297.10731860
Topological Polar Surface Area146 Ų
Heavy Atom Count21
Formal Charge0
Complexity474
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes