AM211

CAT: 0013-GTR19166414-05Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19166414-05Size:25 mg

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Description

AM211 free acid is a potent, orally bioavailable small molecule antagonist of the prostaglandin D2 receptor DP2. It is a valuable research tool for investigating the role of the DP2 receptor in allergic and inflammatory diseases, suitable for both in vitro binding assays and in vivo pharmacological studies.

CAS Number

1175526-27-8

Product Name Alternative

AM 211, AM211, AM-211, AM211 free acid, Prostaglandin Receptor, prostaglandin D2 receptor, ProstaglandinReceptor

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

≥95% (May vary between batches)

Solubility

DMSO:125 mg/mL (249.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.99 mM)

Smiles

CCN (Cc1cc (ccc1-c1cc (CC (O) =O) ccc1OC) C (F) (F) F) C (=O) NCc1ccccc1

Molecular Formula

C27H27F3N2O4

Molecular Weight

500.51

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Am-211

CAS Number	1175526-27-8
PubChem CID	44158492
IUPAC Name	2-[3-[2-[[benzylcarbamoyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid
Molecular Formula	C27H27F3N2O4
Molecular Weight	500.5
XLogP	4.9
Topological Polar Surface Area	78.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Heavy Atom Count	36
Formal Charge	0
Complexity	714

SMILES

CCN(CC1=C(C=CC(=C1)C(F)(F)F)C2=C(C=CC(=C2)CC(=O)O)OC)C(=O)NCC3=CC=CC=C3

InChI

InChI=1S/C27H27F3N2O4/c1-3-32(26(35)31-16-18-7-5-4-6-8-18)17-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(33)34)9-12-24(23)36-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,31,35)(H,33,34)

InChIKey

OPXIRFWNLBDKQB-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1175526-27-8

CID: 44158492

Formula: C27H27F3N2O4

MW: 500.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	500.5
XLogP3	4.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	500.19229183
Monoisotopic Mass	500.19229183
Topological Polar Surface Area	78.9 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	714
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

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GTR19163425-01	AM251
GTR19201397-01	AM281
GTR19173105-01	AM251
GTR19160408-01	AM281

Alternative Products

Catalog	Name
MBS3846039-01	AM211
A21612-10	AM211 10mg
HY-13213A	AM211 (sodium)
A21612-1	AM211 1mg
A21612-100	AM211 100mg
A21612-25	AM211 25mg
A21612-5	AM211 5mg
A21612-50	AM211 50mg
A21612-10mM-D	AM211 10mM * 1mL in DMSO

AM211

Chemical Information

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