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AZ3451

CAT: 0013-GTR19166372-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166372-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ3451 is a potent allosteric antagonist of protease-activated receptor 2 (PAR2), exhibiting an IC50 of 23 nM. This small molecule is a valuable research tool for investigating PAR2-mediated signaling in inflammation, pain, and cancer within in vitro and in vivo experimental models.
CAS Number
2100284-59-9
Product Name Alternative
Thrombin receptors, Proteaseactivated Receptor, Protease Activated Receptor (PAR), Protease-Activated Receptor (PAR), ProteaseactivatedReceptor, AZ 3451, AZ3451, AZ-3451, inhibit, PAR-2, Inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
98.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.77 mM) ; H2O:Insoluble; DMSO:80 mg/mL (139.99 mM)
Smiles
C[C@@H] (C1CCCCC1) n1c (nc2cc (ccc12) C (=O) Nc1ccc (cc1) C#N) -c1cc2OCOc2cc1Br
Molecular Formula
C30H27BrN4O3
Molecular Weight
571.46
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

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