Products for Research Use Only

GNE-495

CAT: 0013-GTR19166313-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166313-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNE-495 is a highly potent and selective small molecule inhibitor of MAP4K4, demonstrating an IC50 of 3.7 nM. This compound is a valuable research tool for investigating MAP4K4's role in cellular signaling, with applications in studying metabolic disorders, cancer biology, and inflammation in both in vitro and in vivo models.
CAS Number
1449277-10-4
Product Name Alternative
GNE 495, GNE495, GNE-495, Inhibitor, MAP4K, MAP4K4, MAPK Kinase Kinase Kinase, inhibit
Field of Research
Signal Transduction
Purity
98.23% (May vary between batches)
Solubility
DMSO:2 mg/mL (4.93 mM)
Smiles
Nc1ncc (C (=O) NC2CN (C2) C (=O) C2CC2) c2ccc (nc12) -c1cccc (F) c1
Molecular Formula
C22H20FN5O2
Molecular Weight
405.42
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.