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LY 3000328

CAT: 0013-GTR19166284-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166284-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY 3000328 is a potent and selective cathepsin S inhibitor, with IC50 values of 7.7 nM (human) and 1.67 nM (mouse) . It is a research tool for studying extracellular matrix remodeling, with applications in investigating abdominal aortic aneurysm (AAA) progression in preclinical models through the inhibition of elastin and collagen degradation.
CAS Number
1373215-15-6
Product Name Alternative
Cathepsin, Cathepsin S, Cathepsin S inhibitor, CysteineProtease, Cysteine Protease, inhibit, LY 3000328, LY3000328, LY-3000328, Inhibitor
Field of Research
Protein Biochemistry
Purity
97.83% (May vary between batches)
Solubility
DMSO:62.5 mg/mL (128.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.13 mM)
Smiles
CNC (=O) O[C@H]1COc2ccc (cc2[C@@H]1NC (=O) c1ccc (F) cc1) N1CCN (CC1) C1COC1
Molecular Formula
C25H29FN4O5
Molecular Weight
484.52
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

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