Products for Research Use Only
RegisterLogin

Vazegepant hydrochloride

CAT: 0013-GTR19165953-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19165953-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Vazegepant hydrochloride is a novel intranasal CGRP receptor antagonist for the acute treatment of migraine, supported by positive Phase II/III clinical data. It is utilized in preclinical research to investigate CGRP-mediated pathways in both in vitro binding assays and in vivo models of migraine and pain.
CAS Number
1414976-20-7
Product Name Alternative
CGRP Receptor, CGRP, CGRPReceptor, COVID-19, BHV 3500, BHV3500, BHV-3500, Calcitonin gene-related peptide receptor, Inhibitor, gepant, inflammation, intranasal, inhibit, migraine, receptor, Zavegepant, soluble, Vazegepant, Vazegepant HCl, Vazegepant hydrochloride, Vazegepant Hydrochloride
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.93% (May vary between batches)
Solubility
DMSO:30 mg/mL (44.42 mM)
Smiles
Cl.CN1CCC (CC1) N1CCN (CC1) C (=O) [C@@H] (Cc1cc (C) c2[nH]ncc2c1) NC (=O) N1CCC (CC1) c1cc2ccccc2[nH]c1=O
Molecular Formula
C36H47ClN8O3
Molecular Weight
675.3
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Zavegepant hydrochloride

Zavegepant hydrochloride is the hydrochloride salt of zavegepant. It is a calcitonin gene-related peptide receptor antagonist administered as a nasal spray for the acute treatment of migraine with or without aura in adults. It has a role as a calcitonin gene-related peptide receptor antagonist. It contains a zavegepant(1+).

CAS Number1414976-20-7
PubChem CID134819878
IUPAC NameN-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide;hydrochloride
Molecular FormulaC36H47ClN8O3
Molecular Weight675.3
Topological Polar Surface Area117
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count48
Formal Charge0
Complexity1160
SMILES
CC1=CC(=CC2=C1NN=C2)C[C@H](C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O.Cl
InChI
InChI=1S/C36H46N8O3.ClH/c1-24-19-25(20-28-23-37-40-33(24)28)21-32(35(46)43-17-15-42(16-18-43)29-9-11-41(2)12-10-29)39-36(47)44-13-7-26(8-14-44)30-22-27-5-3-4-6-31(27)38-34(30)45;/h3-6,19-20,22-23,26,29,32H,7-18,21H2,1-2H3,(H,37,40)(H,38,45)(H,39,47);1H/t32-;/m1./s1
InChIKey
VQDUWCSSPSOSNA-RYWNGCACSA-N
Chemical Structure
2D Structure
2D structure of Zavegepant hydrochloride
CAS: 1414976-20-7
CID: 134819878
Formula: C36H47ClN8O3
MW: 675.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight675.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass674.3459651
Monoisotopic Mass674.3459651
Topological Polar Surface Area117 Ų
Heavy Atom Count48
Formal Charge0
Complexity1160
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19189736-01Vazegepant
GTR19224924-01NSC10010 hydrochloride
GTR19251079-01Tryptamine hydrochloride
GTR19250781Azetidine hydrochloride
GTR19157452-01Benzamil (hydrochloride)
GTR19157233-01Imeglimin hydrochloride
GTR19156886-01Propranolol hydrochloride
GTR19156853-01Dopexamine hydrochloride
GTR19156692-01Poziotinib hydrochloride
GTR19156410-01Naftopidil hydrochloride

Alternative Products

CatalogName
BUP02968-01Vazegepant hydrochloride
T38734-01Vazegepant
JH918843Vazegepant HCl
HY-134992S(Rac) -Vazegepant-13C, d3
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)
OR1043462-01Hydrochloride

Popular Products