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TC-G 1005

CAT: 0013-GTR19165844-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165844-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TC-G 1005 is a highly potent and selective GPBA/TGR5 agonist with an EC50 of 0.72 nM, demonstrating oral bioavailability. It shows selectivity over FXR and has been shown in research to elevate plasma GLP-1 and lower blood glucose levels in murine models, supporting its investigation in metabolic disease research.
CAS Number
1415407-60-1
Product Name Alternative
Inhibitor, levels, G-protein coupled receptor 19, G protein-coupled Bile Acid Receptor 1, glucose, GPBAR1, GPCR19, hTGR5, inhibit, coupled, TC G 1005, TC-G1005, TC-G-1005, TCG 1005, TC-G 1005, Takeda, protein, TGR5
Field of Research
Pharmacology & Drug Discovery
Purity
98.20% (May vary between batches)
Solubility
DMSO:10 mg/mL (25.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.5 mM)
Smiles
Cc1ccc (C) c (Oc2ccncc2C (=O) N2CCN (C3CC3) c3ccccc23) c1
Molecular Formula
C25H25N3O2
Molecular Weight
399.48
Storage Conditions
-20°C
Notes
For research use only.

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