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Inulicin

CAT: 0804-HY-N0896-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0896-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Inulicin (1-O-Acetylbritannilactone) is an active compound that inhibits VEGF-mediated activation of Src and FAK. Inulicin (1-O-Acetylbritannilactone) inhibits LPS-induced PGE2 production and COX-2 expression, and NF-κB activation and translocation.
CAS Number
33627-41-7
Product Name Alternative
1-O-Acetylbritannilactone
UNSPSC
12352005
Hazard Statement
H302
Target
COX; NF-κB
Type
Natural Products
Related Pathways
Immunology/Inflammation; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-O-Acetylbritannilactone.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@](C2=C)([H])[C@@](OC2=O)([H])CC(C)=C1[C@@H](C)CCCOC(C)=O
Molecular Formula
C17H24O5
Molecular Weight
308.37
Precautions
H302
References & Citations
[1]Zhengfu H, et al. 1-o-acetylbritannilactone (ABL) inhibits angiogenesis and lung cancer cell growth through regulating VEGF-Src-FAK signaling. Biochem Biophys Res Commun. 2015 Aug 21;464 (2) :422-7.|[2]Liu YP, et al. Acetylbritannilactone suppresses lipopolysaccharide-induced vascular smooth muscle cell inflammatory response. Eur J Pharmacol. 2007 Dec 22;577 (1-3) :28-34.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; NF-κB

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