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Onjisaponin B

CAT: 0013-GTR19165458-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165458-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Onjisaponin B is a research compound that activates autophagy through the AMPK-mTOR pathway, elevates NGF, and enhances clearance of mutant huntingtin and A53T α-synuclein. It is utilized in preclinical studies for neurodegenerative disease research, including Parkinson's, Alzheimer's, and Huntington's disease models.
CAS Number
35906-36-6
Product Name Alternative
AMPK, Autophagy, Inhibitor, Onjisaponin B, inhibit, mTOR, PGE
Field of Research
Cell Biology, Epigenetics & Chromatin, Neuroscience, Protein Biochemistry, Signal Transduction
Purity
99.20% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.27 mM) ; DMSO:50 mg/mL (31.77 mM)
Smiles
[H][C@@]1 (O[C@H]2[C@H] (C) O[C@@] ([H]) (O[C@H]3[C@H] (OC (=O) [C@]45CCC (C) (C) C[C@@]4 ([H]) C4=CC[C@]6 ([H]) [C@@]7 (C) C[C@H] (O) [C@H] (O[C@]8 ([H]) O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]8O) [C@@] (C) (C (O) =O) [C@]7 ([H]) CC[C@@]6 (C) [C@]4 (CO) CC5) O[C@H] (C) [C@H] (OC (=O) \C=C\c4ccc (OC) cc4) [C@@H]3O[C@]3 ([H]) O[C@@H] (C) [C@H] (O) [C@@H] (O) [C@H]3O) [C@H] (O) [C@@H]2O) OC[C@@H] (O[C@]2 ([H]) O[C@H] (CO) [C@H] (O) [C@H] (O) [C@H]2O) [C@H] (O) [C@H]1O
Molecular Formula
C75H112O35
Molecular Weight
1573.67
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

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