Caulophyllogenin

CAT: 0013-GTR19165345-02Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19165345-02Size:1 mg

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Description

Caulophyllogenin, a natural partial PPARγ agonist (EC50 = 12.6 μM) from Kalopanax pictus, suppresses pro-inflammatory cytokine secretion. This activity supports its research utility in studying metabolic and inflammatory conditions, including type-2 diabetes, obesity, and metabolic syndrome, in both cellular and animal models.

CAS Number

52936-64-8

Product Name Alternative

PPARγ, Segetalic acid, TNF-α, IL Receptor, IL-12, ILReceptor, IL-6, Immunology related, Immunologyrelated, Inflammationrelated, inflammation, Inflammation related, Caulophyllogenin

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology

Purity

98.56% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:100 mg/mL (204.62 mM)

Smiles

C (O) (=O) [C@]12[C@] (C=3[C@@] (C) (C[C@H]1O) [C@@]4 (C) [C@] (CC3) ([C@]5 (C) [C@@] (CC4) ([C@@] (CO) (C) [C@@H] (O) CC5) [H]) [H]) (CC (C) (C) CC2) [H]

Molecular Formula

C30H48O5

Molecular Weight

488.7

Storage Conditions

Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Chemical Information

Caulophyllogenin

Caulophyllogenin is a triterpenoid.

CAS Number	52936-64-8
PubChem CID	104361
IUPAC Name	(4aR,5R,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-5,10-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
Molecular Formula	C30H48O5
Molecular Weight	488.7
XLogP	6.2
Topological Polar Surface Area	98
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Heavy Atom Count	35
Formal Charge	0
Complexity	941

SMILES

C[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H]([C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)O)C)C)(C)CO)O

InChI

InChI=1S/C30H48O5/c1-25(2)13-14-30(24(34)35)19(15-25)18-7-8-21-26(3)11-10-22(32)27(4,17-31)20(26)9-12-28(21,5)29(18,6)16-23(30)33/h7,19-23,31-33H,8-17H2,1-6H3,(H,34,35)/t19-,20+,21+,22-,23+,26-,27-,28+,29+,30+/m0/s1

InChIKey

FABOBEOYNMHSHB-UAWZMHPWSA-N

Chemical Structure

2D Structure

CAS: 52936-64-8

CID: 104361

Formula: C30H48O5

MW: 488.7

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	488.7
XLogP3	6.2
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	488.35017463
Monoisotopic Mass	488.35017463
Topological Polar Surface Area	98 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	941
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BA4472-5	Caulophyllogenin

Caulophyllogenin

Chemical Information

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