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Venadaparib

CAT: 0013-GTR19164816-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164816-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Venadaparib (IDX-1197) is a highly potent and selective oral PARP1/2 inhibitor, demonstrating IC50 values of 1.4 nM and 1.0 nM, respectively. It exhibits no activity against PARP-5. By blocking the repair of DNA single-strand breaks, this inhibitor is a valuable tool for investigating synthetic lethality in various solid tumor models, both in vitro and in vivo.
CAS Number
1681017-83-3
Product Name Alternative
Poly ADP ribose polymerase, solid, Venadaparib, tumors, Inhibitor, IDX 1197, IDX1197, IDX-1197, PARP, PARP2, PARP1, NOV 140101, NOV140101, NOV-140101, inhibit, anticancer
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.47% (May vary between batches)
Solubility
DMSO:90 mg/mL (221.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.3 mM)
Smiles
Fc1ccc (Cc2n[nH]c (=O) c3ccccc23) cc1C (=O) N1CC (CNC2CC2) C1
Molecular Formula
C23H23FN4O2
Molecular Weight
406.45
Storage Conditions
-20°C
Notes
For research use only.

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BA4366-25Venadaparib
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MBS5799676Venadaparib hydrochloride
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