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Thapsigargin

CAT: 0013-GTR19164460-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164460-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thapsigargin is a natural SERCA inhibitor that disrupts calcium homeostasis by blocking Ca2+ uptake into the ER/SR, leading to elevated cytosolic Ca2+ and ER stress. It is widely used in vitro and in vivo to study apoptosis, autophagy, and ER stress signaling pathways in cancer and neurodegenerative disease research.
CAS Number
67526-95-8
Product Name Alternative
Unfolded, protein , response, SARSCoV, SARS coronavirus, SARS-CoV, stress, Thapsigargin, inhibit, Inhibitor, Apoptosis, CalciumChannel, Ca2+ channels, Ca2+-ATPase, Calcium Channel, Ca channels, coronavirus
Field of Research
Cell Biology
Purity
>98%
Bioactivity
SERCA inhibitor
Form
Wax
Solubility
Soluble in DMSO (up to 65 mg/ml) or in Ethanol (up to 20 mg/ml) .
Smiles
O (C (CCCCCCC) =O) [C@H]1[C@]2 (C ([C@]3 ([C@] (O) ([C@@H] (OC (CCC) =O) C[C@@]2 (OC (C) =O) C) [C@] (C) (O) C (=O) O3) [H]) =C (C) [C@@H]1OC (/C (=C\C) /C) =O) [H]
Molecular Formula
C34H50O12
Molecular Weight
650.77
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Isolated from Thapsia garganica

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