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CBL0137

CAT: 0013-GTR19164330-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164330-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CBL0137 (Curaxin CBL0137) is a histone chaperone FACT (facilitates chromatin transcription) and MYC signal inhibitor that markedly reduced tumor initiation and progression in vivo; simultaneously activates p53 and inhibits NF-κB without causing detectable genotoxicity, causes phosphorylation of p53 Ser (392) by CK2 and inhibition of NF-κB-dependent transcription in neuroblastoma cells; eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer.Brain Cancer Phase 1 Clinical.
CAS Number
1197996-80-7
Product Name Alternative
CBL-0137 | CBL 0137 | Curaxin CBL0137 | CBLC 137
Purity
>98% (HPLC)
Smiles
CC (NCCN1C2=C (C3=C1C=CC (C (C) =O) =C3) C=C (C (C) =O) C=C2) C
Molecular Formula
C21H24N2O2
Molecular Weight
336.435
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,1'- (9- (2- (isopropylamino) ethyl) -9H-carbazole-3,6-diyl) bis (ethan-1-one)

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