Products for Research Use Only
RegisterLogin

LRRK2-IN-1

CAT: 0013-GTR19164211-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19164211-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent LRRK2 inhibitor with IC50s of 13 nM/6 nM for wild-type/G2019S mutant LRRK2 repectively (0.1 mM ATP in the assay) ; shows modest activity against LRRK2 A2016T (IC50=2.45 uM) and LRRK2 A2016T+G2019S mutant (IC50=3.08 uM) ; also inhibits DCLK1 (IC50=2.61 nM) and 2 (IC50=45 nM) ; induces dephosphorylation of Ser910 and Ser935 of LRRK2 and alters the cytoplasmic localisation of LRRK2.
CAS Number
1234480-84-2
Product Name Alternative
LRRK 2-IN-1
Field of Research
Cell Biology
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C1N (C) C2=CN=C (NC3=CC=C (C (N4CCC (N5CCN (C) CC5) CC4) =O) C=C3OC) N=C2N (C) C6=CC=CC=C16
Molecular Formula
C31H38N8O3
Molecular Weight
570.6852
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-[[4- (4-methyl-1-piperazinyl) -1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-

Related Products

CatalogName
GTR19212790-01LRRK2/NUAK1/TYK2-IN-1
GTR17691822Phospho-LRRK2/LRRK2 Rabbit Monoclonal Antibody
GTR19218962-01LRRK2-IN-10
GTR19212336-01LRRK2-IN-7
GTR19185018-01LRRK2-IN-4
GTR19184793-01LRRK2-IN-2
GTR18587416-01LRRK2 Antibody
GTR19263248-01LRRK2-IN-19
GTR19258011-01LRRK2-IN-17
GTR18793458LRRK2 Antibody

Alternative Products

CatalogName
A3558-50LRRK2-IN-1

Popular Products