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VX-222

CAT: 0013-GTR19164045-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164045-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective, nonnucleoside inhibitor of HCV NS5B polymerase inhibitor with Kd of 17 nM; inhibits the 1b/Con1 HCV subgenomic replicon with EC50 of 17 nM, the M423I and A486S variants remaine susceptible to VX-222; exhibits non-competitive and selective inhibition in HCV NS5B of genotype 1a and 1b, with IC50 of 0.94 and 1.2 uM, respectively; displays fine pharmacokinetic pro le in rats and dogs.HCV Infection Phase 2 Discontinued.
CAS Number
1026785-59-0
Product Name Alternative
VCH-222 | Lomibuvir
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 32 mg/mL
Smiles
CC1CCC (CC1) C (=O) N (C2CCC (CC2) O) C3=C (SC (=C3) C#CC (C) (C) C) C (=O) O
Molecular Formula
C25H35NO4S
Molecular Weight
445.6147
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Thiophenecarboxylic acid, 5- (3,3-dimethyl-1-butyn-1-yl) -3-[ (cis-4-hydroxycyclohexyl) [ (trans-4-methylcyclohexyl) carbonyl]amino]-

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Alternative Products

CatalogName
MBS3600130-01VX-222
MBS132220-01VX 222
S1480-10mM/1mLLomibuvir (VX-222)
A4032-50VX-222 (VCH-222, Lomibuvir)

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