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Lansoprazole

CAT: 0013-GTR19164015-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164015-01Size:500 mg
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Description
Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid. (In Vitro) :Lansoprazole from 0.3 to 3 μM inhibits gastric acid formation in a concentration-dependent manner (IC50 of 0.76 μM) .Lansoprazole (30-300 μM) both induced concentration-dependent, reversible and reproducible relaxations of arteries. (In Vivo) :Lansoprazole (20-40 mg/kg) treatment significantly attenuated STZ and HFD -induced memory deficits, biochemical and histopathological alterations.Lansoprazole (20 mg/kg and 40 mg/kg, p.o.) significantly reduces the STZ and HFD- induced increase in AChE activity.Lansoprazole (20 mg/kg and 40 mg/kg, p.o.) significantly reduces the STZ and HFD- induced rise in brain MPO level.Further HFD mice treated with lansoprazole (20 mg/kg and 40 mg/kg, p.o.) shows a marked decrease in the body weight in comparison to the control animals.
CAS Number
103577-45-3
Product Name Alternative
AG-1749
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 14 mg/mL (37.9 mM) ; DMSO: 74 mg/mL (200.34 mM)
Smiles
O=S (C1=NC2=CC=CC=C2N1) CC3=NC=CC (OCC (F) (F) F) =C3C
Molecular Formula
C16H14F3N3O2S
Molecular Weight
369.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-[[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl]methylsulfinyl]-1H-benzimidazole

Alternative Products

CatalogName
A1229-1000Lansoprazole

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