Products for Research Use Only

TMP-195

CAT: 0013-GTR19163870-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163870-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A first-in-class, potent, selective class IIa HDACs (HDAC4, HDAC5, HDAC7 and HDAC9) inhibtior with IC50 of 60, 59, 26, and 15 nM, respectively; shows no significant inhibition for others HDACs; alters the tumour microenvironment and reduces tumour burden and pulmonary metastases by modulating macrophage phenotypes in mice; induces the recruitment and differentiation of highly phagocytic and stimulatory macrophages within tumours.
CAS Number
1314891-22-9
Product Name Alternative
TMP 195 | TMP195
Purity
>98% (HPLC)
Solubility
DMSO: 82 mg/mL (179.7 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NCC (C1=COC (C2=CC=CC=C2) =N1) (C) C) C3=CC=CC (C4=NOC (C (F) (F) F) =N4) =C3
Molecular Formula
C23H19F3N4O3
Molecular Weight
456.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2-methyl-2- (2-phenyloxazol-4-yl) propyl) -3- (5- (trifluoromethyl) -1,2,4-oxadiazol-3-yl) benzamide

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