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Poziotinib

CAT: 0013-GTR19163686-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163686-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Poziotinib (HM781-36B, NOV120101) is an irreversible pan-HER inhibitor with IC50 of 3.2/5.3 nM/23.5 nM for HER1/HER2/HER4; inhibits phosphorylation of HER family and downstream signaling molecules, and induced apoptosis and G1 arrest; exerts synergistic effects with chemotherapeutic agents.Breast Cancer Phase 2 Clinical.
CAS Number
1092364-38-9
Product Name Alternative
HM781-36B | NOV120101
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C=CC (N1CCC (OC2=CC3=C (NC4=CC=C (Cl) C (Cl) =C4F) N=CN=C3C=C2OC) CC1) =O
Molecular Formula
C23H21Cl2FN4O3
Molecular Weight
491.3423
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propen-1-one, 1-[4-[[4-[ (3,4-dichloro-2-fluorophenyl) amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-

Alternative Products

CatalogName
HY-15730-01Poziotinib
A13044-100Poziotinib 100mg

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