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CCT 137690

CAT: 0013-GTR19163674-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163674-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C; displays antiproliferative activity in a range of human tumor cell lines, including SW620 colon carcinoma (GI50=0.30 uM) and A2780 ovarian cancer cell line (GI50=0.14 uM) ; exhibits in vivo efficacy with no observed toxicities in SW620 colon carcinoma xenografts.
CAS Number
1095382-05-0
Product Name Alternative
CCT-137690 | CCT137690
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CN1CCN (C2=CC=C (C3=NC4=C (N5CCN (CC6=NOC (C) =C6) CC5) C (Br) =CN=C4N3) C=C2) CC1
Molecular Formula
C26H31BrN8O
Molecular Weight
551.4813
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3H-Imidazo[4,5-b]pyridine, 6-bromo-7-[4-[ (5-methyl-3-isoxazolyl) methyl]-1-piperazinyl]-2-[4- (4-methyl-1-piperazinyl) phenyl]-

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Alternative Products

CatalogName
254907-01CCT 137690
B1935-5CCT-137690

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