Products for Research Use Only
RegisterLogin

MK-571 sodium salt

CAT: 0013-GTR19163575-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19163575-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent and specific LTD4 receptor antagonist with Ki of 0.22 nM; effectively blocks LTD4 activation of recombinant human and mouse CysLT1 receptors; also is an inhibitor of multidrug resistance protein-1 (MRP1) mediated transportorally active.Asthma Phase 2 Clinical (In Vitro) :MK571 (15 μM, 1 h) sodium markedly suppresses constitutive and Ag-stimulated S1P secretion from RBL-2H3 cells and mast cells, and inhibits Fluo-3 efflux. (In Vivo) :MK-571 sodium (0-0.5 mg/kg, orally, once) produces dose-dependent inhibition of the duration of antigen-induced dyspnea in conscious sensitized rats treated with methysergide (3 μg/kg) .MK-571 sodium (0-1 mg/kg, orally, once) blocks LTD4- and Ascaris-induced bronchoconstriction in conscious squirrel monkeys.MK-571 sodium (0-25 mg/kg, Orally, daily, for 2 more weeks) shows reversal of hypoxic pulmonary hypertension (PH), and protects mice from hypoxic PH.
CAS Number
115103-85-0
Product Name Alternative
L-660711 sodium salt
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 33 mg/mL
Smiles
CN (C) C (=O) CCSC (C1=CC=CC (=C1) C=CC2=NC3=C (C=CC (=C3) Cl) C=C2) SCCC (=O) [O-].[Na+]
Molecular Formula
C26H26ClN2NaO3S2
Molecular Weight
537.069
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Propanoic acid, 3-[[[3-[2- (7-chloro-2-quinolinyl) ethenyl]phenyl][[3- (dimethylamino) -3-oxopropyl]thio]methyl]thio]-, sodium salt, (E) - (9CI)

Related Products

CatalogName
GTR19194684-01MK-571 sodium
GTR19167351-01MK-571
GTR19205391-01MK-2894 sodium salt
GTR19209373-01MK-886 sodium salt
GTR19198824-01MK-0752 Sodium
GTR19193518-01MK-0952 Sodium
GTR19197272LFF 571
GTR19275000-01CK-571
GTR19156836-01Nigericin sodium salt
GTR19155266-01Resorufin sodium salt

Alternative Products

CatalogName
T22351-01MK-571 sodium salt
BML-RA109-0025MK-571 . sodium salt
A15983-25MK-571 sodium salt 25mg
A15983-10MK-571 sodium salt 10mg
sc-218859MK-571-d6 Sodium Salt
B8031-10MK-571 sodium salt hydrate
A15983-50MK-571 sodium salt 50mg
A15983-5MK-571 sodium salt 5mg
A15983-100MK-571 sodium salt 100mg
A15983-10mM-DMK-571 sodium salt 10mM * 1mL in DMSO

Popular Products