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Riluzole

CAT: 0013-GTR19163496-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163496-01Size:50 mg
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Description
Riluzole is a sodium channel protein inhibitor and potent neuroprotective agent. It has been shown to preferentially block tetrodotoxin-sensitive sodium channels, which are associated with damaged neurons. In the presence of negative potentials, Riluzole was shown to also block tetrodotoxin-resistant sodium channels. It has been reported that Riluzole exerts its neuroprotective action under ischemic conditions, thereby suppressing glutamatergic receptor stimulation and calcium influx. Research shows that this product activates the TREK family of potassium channels and directly affects the glutamatergic system. Riluzole inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Riluzole blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes.
CAS Number
1744-22-5
Product Name Alternative
Riluzole, Rilutek, PK 26124, RP 54274
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 47 mg/mL (200.68 mM) ; DMSO: 47 mg/mL (200.68 mM)
Smiles
NC1=NC2=CC=C (OC (F) (F) F) C=C2S1
Molecular Formula
C8H5F3N2OS
Molecular Weight
234.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6- (trifluoromethoxy) -1,3-benzothiazol-2-amine

Alternative Products

CatalogName
S1614-1gRiluzole

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