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Xylocaine

CAT: 0013-GTR19163371-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19163371-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx. (In Vitro) :Lidocaine (Lignocaine) (10 nM; 48 hours) decreases significantly cell proliferation.Lidocaine (1-10 nM; 24-72 hours) inhibits cell viability and achieves the most suppressing effects at the concentration of 10 nM and treatment time 48 hours.Lidocaine (10 nM; 48 hours) increases significantly the apoptotic cell rate.Lidocaine (10 nM; 48 hours) down-regulates Cyclin D1 and up-regulates p21 expression significantly. (In Vivo) :Lidocaine (Lignocaine) causes completely reversible tail nerve block in rats. Mechanical nociception block produced by lidocaine has slower onset and faster recovery compared with thermal nociception block.
CAS Number
137-58-6
Product Name Alternative
NSC 40030
Purity
>98% (HPLC)
Solubility
Ethanol: 47 mg/mL (200.56 mM) ; Water: 9 mg/mL (38.4 mM) ; DMSO: 47 mg/mL (200.56 mM)
Smiles
O=C (NC1=C (C) C=CC=C1C) CN (CC) CC
Molecular Formula
C14H22N2O
Molecular Weight
234.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2',6'-Acetoxylidide, 2- (diethylamino) -

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