Products for Research Use Only

Deflazacort

CAT: 0013-GTR19163191-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163191-01Size:100 mg
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Description
Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.It suppresses the immune system and so it can be used to treat autoimmune diseases. Deflazacort can help to prevent and to treat the rejection of transplanted organs. It can also be used in the treatment of certain types of Ys. (In Vitro) :Deflazacort is an inactive prodrug which is converted rapidly to the active metabolite 21-desacetyldeflazacort. Maximum concentrations of 21-desacetyldeflazacort averaged 116 ng/ml and were observed after 1.3 h. The average area under the curve was 280 ng/ml.h, and the terminal half-life was 1.3 h. 21-Desacetyldeflazacort was cleared significantly faster than both methylprednisolone and prednisolone.
CAS Number
14484-47-0
Product Name Alternative
DL-458IT | L-5,458 | MDL 458
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 12 mg/mL (27.17 mM) ; DMSO: 88 mg/mL (199.31 mM)
Smiles
CC (OCC (C12N=C (C) OC1CC3C (CCC4=CC (C=C[C@@]45C) =O) C5[C@@H] (O) C[C@@]32C) =O) =O
Molecular Formula
C25H31NO6
Molecular Weight
441.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- ((6aR,7S,8aS) -7-hydroxy-6a,8a,10-trimethyl-4-oxo-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl) -2-oxoethyl acetate

Alternative Products