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ML-323

CAT: 0013-GTR19163015-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163015-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective, reversible inhibitor of the USP1/UAF1 deubiquitinase complex with IC50 of 76 nM; displays >1,500-fold selectivity versus USP2, USP5, USP7, USP8, and USP46/UAF1; potentiates the cytotoxicity of cisplatin and increases endogenous monoubiquitination levels of both PCNA and FANCD2, two known cellular targets of USP1/UAF1; possesses a promising in vitro ADME profile.
CAS Number
1572414-83-5
Product Name Alternative
ML323 | ML 323
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 49 mg/mL
Smiles
CC1=CN=C (C2=CC=CC=C2C (C) C) N=C1NCC3=CC=C (N4N=NC=C4) C=C3
Molecular Formula
C23H24N6
Molecular Weight
384.4769
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4- (1H-1,2,3-triazol-1-yl) benzyl) -2- (2-isopropylphenyl) -5-methylpyrimidin-4-amine

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Alternative Products

CatalogName
B1317-25ML-323
BM166458-01ML 323
A14030-100ML-323 100mg
A14030-50ML-323 50mg
A14030-10ML-323 10mg
A14030-1ML-323 1mg
A14030-25ML-323 25mg
A14030-5ML-323 5mg
TBI1560-5MGML-323, USP1-UAF1 inhibitor
A14030-10mM-DML-323 10mM * 1mL in DMSO

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