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NU-2058

CAT: 0013-GTR19162983-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162983-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
An ATP-competitive inhibitor of CDK1 and CDK2 with Ki of 5 uM and 12 uM respectively; inhibits human tumor cells with a mean GI50 of 13±7 uM; reduces CDK2-mediated phosphorylation of pRb, E2F transcriptional activity and proliferatio in both anti-estrogen-sensitive and resistant cells; also inhibits DNA topoisomerase II ATPase activity (IC50=300 uM) .
CAS Number
161058-83-9
Product Name Alternative
O6-cyclohexylmethyl guanine | NU2058 | NU 2058
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 32 mg/mL
Smiles
NC1=NC (OCC2CCCCC2) =C3N=CNC3=N1
Molecular Formula
C12H17N5O
Molecular Weight
247.2963
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9H-Purin-2-amine, 6- (cyclohexylmethoxy) -

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