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UNC0379

CAT: 0013-GTR19162963-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162963-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 with IC50 of 7.3 uM, displays good selectivity over 15 other methyltransferases, including G9a and GLP (IC50>100 uM) ; causes neuroblastoma (NB) cell growth inhibition which is p53 dependent, reduces levels of p53K382me1 modification in xenografts.
CAS Number
1620401-82-2
Product Name Alternative
UNC 0379 | UNC-0379
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
COC1=C (OC) C=C (N=C (N2CCCC2) N=C3NCCCCCN4CCCC4) C3=C1
Molecular Formula
C23H35N5O2
Molecular Weight
413.5563
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-Quinazolinamine, 6,7-dimethoxy-2- (1-pyrrolidinyl) -N-[5- (1-pyrrolidinyl) pentyl]-

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