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Cortexolone 17 alpha-propionate

CAT: 0013-GTR19162897-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162897-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo.Other Indication Phase 3 Clinical (In Vivo) :Clascoterone is a new potent topical antiandrogen potentially useful in acne vulgaris. Clascoterone 1% cream was very well tolerated, and was significantly better than placebo regarding TLC (P = 0·0017), ILC (P = 0·0134) and ASI (P = 0·0090), and also clinically more effective than comparator. The product also induced a faster attainment of 50% improvement in all the above parameters.
CAS Number
19608-29-8
Product Name Alternative
Cortexolone 17α-propionate | CB-03-01 | Clascoterone
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CCC (O[C@]1 (C (CO) =O) CC[C@@]2 ([H]) [C@]3 ([H]) CCC4=CC (CC[C@]4 (C) [C@@]3 ([H]) CC[C@]12C) =O) =O
Molecular Formula
C24H34O5
Molecular Weight
402.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Pregn-4-ene-3,20-dione, 21-hydroxy-17- (1-oxopropoxy) -

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