L-779450

CAT: 0013-GTR19162667-01Size: 200 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19162667-01Size:200 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

L-779450 is a potent, ATP-competitive Raf kinase inhibitor with IC50 of 10 nM, displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively; suppresses DNA synthesis and induced apoptosis in hematopoietic FDC-P1 cells transformed to grow in response to either Raf-1 or A-Raf, L-779,450 is less effective on B-Raf- or MEK1-responsive cells, also suppresses DNA synthesis and induces apoptosis in Raf-responsive cells and the effects are more significant on Raf-responsive compared to cytokine-mediated growth.

CAS Number

303727-31-3

Product Name Alternative

L779450

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 34 mg/mL

Smiles

OC1=CC (C2=C (C3=CC=NC=C3) NC (C4=CC=CC=C4) =N2) =CC=C1Cl

Molecular Formula

C20H14ClN3O

Molecular Weight

347.7977

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Phenol, 2-chloro-5-[2-phenyl-4- (4-pyridinyl) -1H-imidazol-5-yl]-

Related Products

Catalog	Name
GTR19067953-01	A-L-A-L
GTR19037261-01	L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine
GTR18896244-01	A-L-A-L peptide
GTR19201185-01	L-CCG-l
GTR19202675-01	L, L-Dityrosine
GTR18889686	A-L-alpha L peptide
GTR19202672	L-Valyl-L-phenylalanine
GTR19207988	L-Homopropargylglycine (L-HPG)
GTR19207987	L-Homopropargylglycine (L-HPG)
GTR18918932	L-Leucyl-L-alanine

Alternative Products

Catalog	Name
406667	L-779450
FL24820-01	L 779450
A13525-10	L-779450 10mg
A13525-100	L-779450 100mg
A13525-5	L-779450 5mg
A13525-2	L-779450 2mg
A13525-50	L-779450 50mg
A13525-25	L-779450 25mg
A13525-10mM-D	L-779450 10mM * 1mL in DMSO
CCP1053-01	A-L-A-L

L-779450

Related Products

Alternative Products

Popular Products