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GRA Ex-25

CAT: 0013-GTR19162644-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162644-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent glucagon receptor inhibitor with IC50 of 56 and 55 nM for rat and human glucagon receptors; binds to human glucagon receptor with Ki of 63 nM, moderately inhibits glucagon induced adenylate cyclase (Ki=254 nM) ; significantly reduces blood glucose caused by exogenous administration of glucagon in rat model (3 mg/kg, i.v.) .Diabetes Preclinical.
CAS Number
307983-31-9
Product Name Alternative
GRA Ex-25 | GRA Ex 25 | GRA Ex25 | GRAEx-25
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 32 mg/mL
Smiles
C[C@] (C1CC[C@H] (N (C (NC2C=CC (OC (F) (F) F) =CC=2) =O) CC2C=CC (C (NCCC (O) =O) =O) =CC=2) CC1) (C) C
Molecular Formula
C29H36F3N3O5
Molecular Weight
563.6085
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
β-Alanine, N-[4-[[[trans-4- (1,1-dimethylethyl) cyclohexyl][[[4- (trifluoromethoxy) phenyl]amino]carbonyl]amino]methyl]benzoyl]-

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