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STF-62247

CAT: 0013-GTR19162618-07Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162618-07Size:200 mg
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Description
STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells; induces cytotoxicity and reduces tumor growth in VHL-deficient cells in a HIF-independent manner, PI3K and Golgi trafficking are required as initial signals in STF-62247-induced autophagy.Kidney Cancer Preclinical.
CAS Number
315702-99-9
Product Name Alternative
STF62247 | STF 62247
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 31 mg/mL
Smiles
CC1=CC (NC2=NC (C3=CC=NC=C3) =CS2) =CC=C1
Molecular Formula
C15H13N3S
Molecular Weight
267.3488
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Thiazolamine, N- (3-methylphenyl) -4- (4-pyridinyl) -

Chemical Information

Stf-62247

N-(3-methylphenyl)-4-pyridin-4-yl-2-thiazolamine is a substituted aniline.

CAS Number315702-99-9
PubChem CID704473
IUPAC NameN-(3-methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine
Molecular FormulaC15H13N3S
Molecular Weight267.4
XLogP3.8
Topological Polar Surface Area66.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count19
Formal Charge0
Complexity281
SMILES
CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3
InChI
InChI=1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18)
InChIKey
KATNUHQNJGNLPW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Stf-62247
CAS: 315702-99-9
CID: 704473
Formula: C15H13N3S
MW: 267.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight267.4
XLogP33.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass267.08301860
Monoisotopic Mass267.08301860
Topological Polar Surface Area66.1 Ų
Heavy Atom Count19
Formal Charge0
Complexity281
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS131509STF-62247 (STF62247; STF 62247)
B2151-25STF-62247

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