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L-Cycloserine

CAT: 0013-GTR19163501-07Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163501-07Size:100 mg
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Description
L-cycloserine irreversibly inhibit GABA pyridoxal 5′-phosphate-dependent aminitransferase in E. coli, as well in the brains of various animals in a time-dependent manner, results in increased levels of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in vivo.
CAS Number
339-72-0
Product Name Alternative
(-) -Cycloserine | (S) -Cycloserine | L-4-amino 3-Isoxazolidinone | Levcycloserine
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Soluble in Water
Smiles
O=C1NOCC1N
Molecular Formula
C3H6N2O2
Molecular Weight
102.09
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-aminoisoxazolidin-3-one

Chemical Information

Levcycloserine

L-cycloserine is a 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora. It has a role as an anticonvulsant, an EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor and an anti-HIV agent. It is an enantiomer of a D-cycloserine.

CAS Number339-72-0
PubChem CID449215
IUPAC Name(4S)-4-amino-1,2-oxazolidin-3-one
Molecular FormulaC3H6N2O2
Molecular Weight102.09
XLogP-1.5
Topological Polar Surface Area64.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count7
Formal Charge0
Complexity92
SMILES
C1[C@@H](C(=O)NO1)N
InChI
InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKey
DYDCUQKUCUHJBH-REOHCLBHSA-N
Chemical Structure
2D Structure
2D structure of Levcycloserine
CAS: 339-72-0
CID: 449215
Formula: C3H6N2O2
MW: 102.09
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight102.09
XLogP3-1.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass102.042927438
Monoisotopic Mass102.042927438
Topological Polar Surface Area64.4 Ų
Heavy Atom Count7
Formal Charge0
Complexity92.9
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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