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Urapidil

CAT: 0013-GTR19163213-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163213-01Size:500 mg
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Description
Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist. (In Vitro) :Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist. Urapidil does not affect vascular tone at concentrations up to 10-5 M. Urapidil (10-5 M) markedly inhibits the alpha 1-adrenergic agonist (phenylephrine) -induced concentration-dependent contractions in aortic rings without endothelium and also to some extent in those with endothelium. Moreover, the inhibitory effect of Urapidil is more pronounced in rings without endothelium than in those with endothelium. Urapidil (10-5 M) affects neither the vascular tone nor the concentration-dependent contraction to serotonin.
CAS Number
34661-75-1
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
CN1C (=CC (=O) N (C1=O) C) NCCCN2CCN (CC2) C3=CC=CC=C3OC
Molecular Formula
C20H29N5O3
Molecular Weight
387.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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