Products for Research Use Only

Doxycycline hyclate

CAT: 0013-GTR19162520-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162520-01Size:100 mg
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Description
Doxycycline Hyclate is a synthetic tetracycline derivative with similar antimicrobial activity. (In Vitro) :Doxycycline hyclate (0.01-10 μg/mL, 4 d) affects growth of glioma cells only under high concentrations.Doxycycline hyclate (0.01-10 μg/mL, 24 h) decreases MT-CO1 protein content with concentrations of 1 μg/mL and higher in SVG cells.Doxycycline hyclate (100 ng/mL, 1 μg/mL; 24 h) reduces proliferation of human cell lines.Doxycycline hyclate (0-250 μM, 72 h) inhibits cell viability of breast cancer cells . (In Vivo) :Doxycycline hyclate (oral gavage; 200 or 800 mg/kg; once daily; 3 months) reduces MMP-9 activity in untreated HT mice in a dose-dependent manner.
CAS Number
24390-14-5
Product Name Alternative
WC 2031
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 100 mg/mL (194.95 mM) ; DMSO: 100 mg/mL (194.95 mM)
Smiles
CCO.C[C@@H]1[C@H]2[C@@H] ([C@H]3[C@@H] (C (=O) C (=C ([C@]3 (C (=O) C2=C (C4=C1C=CC=C4O) O) O) O) C (=O) N) N (C) C) O.C[C@@H]1[C@H]2[C@@H] ([C@H]3[C@@H] (C (=O) C (=C ([C@]3 (C (=O) C2=C (C4=C1C=CC=C4O) O) O) O) C (=O) N) N (C) C) O.O.Cl.Cl
Molecular Formula
C22H24N2O8·HCl·1/2C2H6O·1/2H2O
Molecular Weight
512.9
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(4S,4aR,5S,5aR,6R,12aR) -4- (dimethylamino) -1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide; ethanol; hydrate; dihydrochloride