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Homoharringtonine

CAT: 0013-GTR19162441-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162441-01Size:200 mg
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Description
Homoharringtonine is an alkaloid inhibitor of protein synthesis with activity in myeloid malignancies. It might have clinical activity in some patients with myelodysplastic syndrome . Homoharringtonine enhances the paracellular permeability of Caco-2 cell monolayers by modulating the protein expression and localization of claudin isoforms. Homoharringtonine has anti-Y and antileukemic activities, may have the potential ability to treat acute, chronic myeloid leukaemia and Gefitinib-resistant NSCLC.
CAS Number
26833-87-4
Product Name Alternative
NSC 141633 | Omacetaxine Mepesuccinate
Purity
>98% (HPLC)
Solubility
Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Smiles
COC1=C[C@@]23[C@H] (c4cc (OCO5) c5cc4CCN2CCC3) [C@@H]1OC ([C@] (O) (CCCC (C) (C) O) CC (OC) =O) =O
Molecular Formula
C29H39NO9
Molecular Weight
545.61
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -1- ((11bS,12S,14aR) -13-methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-yl) 4-methyl 2-hydroxy-2- (4-hydroxy-4-methylpentyl) succinate

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