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Piroxicam

CAT: 0013-GTR19162369-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162369-01Size:500 mg
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Description
Piroxicam is a non-selective COX inhibitor. (In Vitro) :Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively. Piroxicam (CP-16171) (167, 333, 500 μM) decreases cell population of T24 and the 5637 cells. Piroxicam (CP-16171) (500 μM) also reduces the cell viability of T24 and 5637 cell, and is significantly effective when combined with 0.05 μM carboplatin. The combination also inhibits Ki-67 expression in booth cells. (In Vivo) :Piroxicam (CP-16171) (0.3 mg/kg qd 24-h p.o.) reduces tumor volume in 12 of 18 dogs, and such and effect is via induction of apoptosis and reduction in urine basic fibroblast growth factor concentration.
CAS Number
36322-90-4
Product Name Alternative
Feldene | Larapam | NSC 666076
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 1 mg/mL (3.01 mM) ; DMSO: 66 mg/mL (199.18 mM)
Smiles
CN1C (=C (C2=CC=CC=C2S1 (=O) =O) O) C (=O) NC3=CC=CC=N3
Molecular Formula
C15H13N3O4S
Molecular Weight
331.35
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

Alternative Products

CatalogName
sc-200576Piroxicam

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