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Diazoxide

CAT: 0013-GTR19162361-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162361-01Size:200 mg
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Description
Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. (In Vitro) :Diazoxide (Sch-6783) has a number of physiological effects, including lowering the blood pressure and rectifying hypoglycemia. Diazoxide has powerful protective properties against cardiac ischemia.Diazoxide (Sch-6783) could protect NSC-34 neurons against the main sources of neurodegenerative damage. Diazoxide increases Nrf2 nuclear translocation in NSC-34 motoneurons and prevents endogenous oxidative damage. (In Vivo) :Diazoxide (Sch-6783) attenuates postresuscitation brain injury, protects mitochondrial function, inhibits brain cell apoptosis, and activates the PKC pathway by opening mitoKATP channels.Treatment with Diazoxide (Sch-6783) in wild-type mice decreases intraocular pressure (IOP) by 21.5±3.2% with an absolute IOP reduction of 3.9 ± 0.6 mm Hg.
CAS Number
364-98-7
Product Name Alternative
NSC 64198 | NSC 76130 | SRG 95213
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
CC1=NS (=O) (=O) C2=C (N1) C=CC (Cl) =C2
Molecular Formula
C8H7ClN2O2S
Molecular Weight
230.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
B6526-100Diazoxide

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