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Vacquinol-1

CAT: 0013-GTR19162082-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162082-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vacquinol-1 (NSC 13316) is a MKK4 (MAP2K4, MEK4) activator that induces vacuolization, induces ATP depletion in glioblastoma cells (IC50 = 3.14 uM) without affecting fibroblasts, embryonic stem cells, or osteosarcoma cells; induces rapid and specific cell death of glioma cells via membrane ruffling, cell rounding, massive macropinocytic vacuole accumulation, ATP depletion, and cytoplasmic membrane rupture; shows good brain penetrance and excellent pharmacokinetics; orally bioactive.
CAS Number
5428-80-8
Product Name Alternative
NSC 13316
Purity
>98% (HPLC)
Solubility
Ethanol: <1 mg/mL; DMSO: 70 mg/mL (164.4 mM) ; Water: <1 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
ClC1=CC=C (C2=NC (C=CC=C3) =C3C (C (O) C4NCCCC4) =C2) C=C1
Molecular Formula
C21H21ClN2O
Molecular Weight
352.862
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
[2- (4-Chlorophenyl) quinolin-4-yl] (piperidine-2-yl) methanol

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558277Vacquinol-1
HY-19345A-01Vacquinol-1 (dihydrochloride)
A15883-50Vacquinol-1 50mg
A15883-25Vacquinol-1 25mg
A15883-10Vacquinol-1 10mg
A15883-100Vacquinol-1 100mg
A15883-5Vacquinol-1 5mg
A15883-1Vacquinol-1 1mg
OF59775-011,1,1,1,1-Kestoheptaose
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