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Metyrapone

CAT: 0013-GTR19162078-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19162078-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Metyrapone is an inhibitor of cytochrome P450-mediated ω/ω-1 hydroxylase activity and CYP11B1. (In Vitro) :Metyrapone (100 μM; 2 h) hyperactivates autophagy in HepG2, and delays the activation of apoptosis at severe endoplasmic reticulum (ER) stress. (In Vivo) :Metyrapone (25 or 50 mg/kg; SC, single dosage) decreases the stress-induced increase in plasma corticosterone levels, significantly impairs acquisition performance at high dosage, and increases open arm activity at low dosage.
CAS Number
54-36-4
Product Name Alternative
NSC 25265 | SU 4885
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Sparingly soluble in Water
Smiles
CC (C1=CC=CN=C1) (C) C (C2=CC=CN=C2) =O
Molecular Formula
C14H14N2O
Molecular Weight
226.27
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-methyl-1,2-dipyridin-3-ylpropan-1-one

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