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AMG-9810

CAT: 0013-GTR19162073-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19162073-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective and competitive TRPV1 antagonist with IC50 of 24.5 and 85.6 nM for human and rat TRPV1, repectively; blocks capsaicin-evoked depolarization and CGRP release in cultures of rat dorsal root ganglion primary neurons; the first cinnamide TRPV1 antagonist reported to block capsaicin-induced eye wiping behavior and reverse hyperalgesia in an animal model of inflammatory pain.Pain Preclinical.
CAS Number
545395-94-6
Product Name Alternative
AMG9810 | AMG 9810
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 33 mg/mL
Smiles
CC (C) (C) c1ccc (cc1) /C=C/C (=O) Nc2ccc3c (c2) OCCO3
Molecular Formula
C21H23NO3
Molecular Weight
337.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propenamide, N- (2,3-dihydro-1,4-benzodioxin-6-yl) -3-[4- (1,1-dimethylethyl) phenyl]-, (2E) -

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