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Embelin

CAT: 0013-GTR19162043-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162043-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Embelin (Embelic acid, Emberine, NSC-91874) is a cell-permeable benzoquinone compound that exhibits antitumor properties; specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50=4.1 uM) ; has anti-inflammatory activities in both acute and chronic irritant contact dermatitis in vivo; also inhibits plasminogen activator inhibitor-1 (PAI-1) with IC50 of 1.62 uM. (In Vitro) :Embelin (Embelic acid) has a minimal effect on normal prostate epithelial and fibroblast cells with low levels of XIAP.
CAS Number
550-24-3
Product Name Alternative
Embelic acid | Emberine | NSC-91874
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCC1=C (C (=O) C=C (C1=O) O) O
Molecular Formula
C17H26O4
Molecular Weight
294.3859
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl-

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