Products for Research Use Only

Naftopidil

CAT: 0013-GTR19161964-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161964-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Naftopidil (INN, marketed under the brand name Flivas) is an antihypertensive drug which acts as a selective α1-adrenergic receptor antagonist or alpha blocker. (In Vitro) :Naftopidil suppresses human prostate tumor growth by altering interactions between tumor cells and stroma.Naftopidil (10 μM for PCa cells, 0.1-10 μM for PrSC; 3 days) shows growth inhibitory effects on PCa cells and PrSC.Naftopidil (50 μM for E9 cells, 25 μM for PrSC; 48 hours) increases the level of cell-cycle regulatory protein p27 in E9 cells, but not PrSC. (In Vivo) :Naftopidil (10 mg/kg; p.o; daily; for 28 days) decreases microvessel density (MVD) in E9+PrSC tumors mice model.
CAS Number
57149-07-2
Product Name Alternative
Naftopidil | BM-15275 | KT-611 | BM 15275 | KT 611 | BM15275 | KT611 | Flivas
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 79 mg/mL (201.27 mM)
Smiles
OC (COC1=C2C=CC=CC2=CC=C1) CN3CCN (C4=CC=CC=C4OC) CC3
Molecular Formula
C24H28N2O3
Molecular Weight
392.49
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (4- (2-methoxyphenyl) piperazin-1-yl) -3- (naphthalen-1-yloxy) propan-2-ol

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