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Pamapimod

CAT: 0013-GTR19161962-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19161962-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective, orally bioavailable p38α MAPK inhibitor with Kd of 0.2 nM; displays >100 fold selectivity over p38β (Kd=29 nM), and no affinity against p38γ, p38δ and a broad panel of kianses; inhibits LPS-stimulated TNF-alpha production by monocytes, IL-1beta production in human whole blood; exhibits the ability to inhibit the signs and symptoms of RA and other autoimmune diseases.Rheumatoid Arthritis Phase 2 Discontinued.
CAS Number
449811-01-2
Product Name Alternative
Ro4402257 | R1503
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 34 mg/mL
Smiles
O=C1C (OC2=CC=C (F) C=C2F) =CC3=CN=C (NC (CCO) CCO) N=C3N1C
Molecular Formula
C19H20F2N4O4
Molecular Weight
406.3833
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Pyrido[2,3-d]pyrimidin-7 (8H) -one, 6- (2,4-difluorophenoxy) -2-[[3-hydroxy-1- (2-hydroxyethyl) propyl]amino]-8-methyl-

Alternative Products

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C13200-01Pamapimod
WZB81457-01Pamapimod-d4
A13551-25Pamapimod 25mg
A13551-5Pamapimod 5mg
HY-10405R-01Pamapimod (Standard)
A13551-10Pamapimod 10mg
MBS131355Pamapimod (R-1503)

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