Products for Research Use Only

Arbutin

CAT: 0013-GTR19161869-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19161869-01Size:1 g
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Description
Arbutin (β-Arbutin) is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos; inhibits tyrosinase and thus prevents the formation of melanin. (In Vitro) :Arbutin (0.3-5.4 mM; 24 hours, 48 hours, 72 hours; B16 murine melanoma cells) inhibites the viability of B16 murine melanoma cells in a time-and dose-dependent manner.Arbutin (1.4-5.4 mM; 24 hours) increases the apoptosis rate of B16 murine melanoma cell of treatment at a dose of 5.4 mM. (In Vivo) :Arbutin (50 mg/kg, 100 mg/kg; oral administration; every day; for 17 days; male C57BL/6 mice) pretreatment exhibits markedly protective effects on ISO-induced cardiac hypertrophy in mice.
CAS Number
497-76-7
Product Name Alternative
β-Arbutin | NSC 4036
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 55 mg/mL (202.02 mM) ; DMSO: 55 mg/mL (202.02 mM)
Smiles
O[C@H] ([C@H] ([C@@H] ([C@@H] (CO) O1) O) O) [C@@H]1OC2=CC=C (O) C=C2
Molecular Formula
C12H16O7
Molecular Weight
272.25
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2R,3S,4S,5R,6S) -2- (hydroxymethyl) -6- (4-hydroxyphenoxy) tetrahydro-2H-pyran-3,4,5-triol