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UMI-77

CAT: 0013-GTR19161753-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161753-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective Mcl-1 inhibitor with Ki of 0.49 uM; displays >10 fold selectivity against Bcl-w, Bfl-1, Bcl-xL and Bcl-2; inhibits cell growth and induces apoptosis in pancreatic cancer cells; blocks the heterodimerization of Mcl-1/Bax and Mcl-1/Bak in cells; inhibits tumor growth in BxPC-3 xenograft model.
CAS Number
518303-20-3
Product Name Alternative
UMI-77, UMI77, UMI 77
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 28 mg/mL
Smiles
C1=CC=C2C (=C1) C (=CC (=C2O) SCC (=O) O) NS (=O) (=O) C3=CC=C (C=C3) Br
Molecular Formula
C18H14BrNO5S2
Molecular Weight
468.3415
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Acetic acid, 2-[[4-[[ (4-bromophenyl) sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]-

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Alternative Products

CatalogName
HY-18628-01UMI-77
HY-18628S-01UMI-77-d4

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