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Toradol

CAT: 0013-GTR19161605-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161605-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor with strong analgesic activity. (In Vitro) :Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. (In Vivo) :Ketorolac tromethamine (0.4%) causes nearly complete inhibition on LPS endotoxin-induced increases in FITC-dextran in the anterior chamber, and increases in aqueous PGE2 concentrations in the aqueous humor in rabbits. Ketorolac (30 mg/kg, i.v.) rapidly reverses hyperalgesia in rats. Ketorolac also reduces carrageenan-induced hyperalgesia and paw PG production, and causes reduction in PGE2 levels in rats. Ketorolac (4 mg/kg/day, p.o.) has no detrimental effect in the volume fraction of bone trabeculae formed inside the alveolar socket in rats. Ketorolac (60 μg/10 μL) reduces the histological changes such as ischemic cell death, including cytoplasmic eosinophilia with disintegration of cytoarchitecture and nuclear pyknosis in rats. Ketorolac also effectively reduces neuronal death and improves hindlimb motor function, and the long-term survival is similar to that in the control group.
CAS Number
74103-07-4
Product Name Alternative
Toradol
Purity
>98% (HPLC)
Solubility
Ethanol: 75 mg/mL warmed (293.8 mM) ; DMSO: 75 mg/mL (293.8 mM)
Smiles
O=C (C1C2=CC=C (C (C3=CC=CC=C3) =O) N2CC1) O.OCC (CO) (N) CO
Molecular Formula
C19H24N2O6
Molecular Weight
376.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-amino-2- (hydroxymethyl) propane-1,3-diol 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate

Alternative Products

CatalogName
MBS575662Toradol

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