Products for Research Use Only

Zaltoprofen

CAT: 0013-GTR19161589-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161589-01Size:500 mg
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Description
Zaltoprofen is an inhibitor of Cox-1 and Cox-2 for treatment of arthritis. (In Vitro) :Zaltoprofen (0.1-10 μM; 15 min) inhibits thromboxane B2 production in human platelets in a dose-dependent manner.Zaltoprofen (0.01-1 μM; 30 min) inhibits prostaglandin E2 production by interleukin-1β-stimulated synovial cells.Zaltoprofen (0.1-1 μM; 5 min) inhibits the bradykinin-induced increase of [Ca2+]i in DRG cells. (In Vivo) :Zaltoprofen (5-20 mg/kg; a single p.o.) inhibits bradykinin-induced nociceptive responses in rats.Zaltoprofen (3-30 mg/kg; a single p.o.) inhibits the acetic acid-induced writhing response of mice in a dose-dependent manner.
CAS Number
74711-43-6
Product Name Alternative
CN 100 | Soleton
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 31 mg/mL (103.9 mM) ; DMSO: 60 mg/mL (201.09 mM)
Smiles
O=C (O) C (C) C1=CC=C (C (C2) =C1) SC3=CC=CC=C3C2=O
Molecular Formula
C17H14O3S
Molecular Weight
298.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
10,11-Dihydro-alpha-methyl-10-oxodibenzo (b, f) thiepin-2-acetic acid

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