Products for Research Use Only

Nizatidine

CAT: 0013-GTR19162435-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162435-01Size:100 mg
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Description
Nizatidine is a histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. (In Vivo) :Nizatidine (oral gavage; 27 mg/kg; once daily; at 12 weeks of age and were sacrificed at 30 weeks after development of HCC in the setting of nonalcoholic steatohepatitis (NASH) ) results in a 35% reduction of tumor nodules relative to controls. Nizatidine results in a 60% reduction in tumor nodules, reduces collagen proportional area and expression of profibrotic markers in DEN-injured rats.Nizatidine (oral gavage; 27 mg/kg; once daily; 4 weeks) decreases the incidence of gastric ulceration, and significantly decreases the mean ulcer score and ulcer index in male albino rats.
CAS Number
76963-41-2
Product Name Alternative
LY139037
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 18 mg/mL (54.3 mM) ; Water: 28 mg/mL (84.47 mM) ; DMSO: 66 mg/mL (199.11 mM)
Smiles
CN/C (NCCSCC1=CSC (CN (C) C) =N1) =C\[N+] ([O-]) =O
Molecular Formula
C12H21N5O2S2
Molecular Weight
331.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -N- (2- (((2- ((dimethylamino) methyl) thiazol-4-yl) methyl) thio) ethyl) -N-methyl-2-nitroethene-1,1-diamine