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Terbinafine hydrochloride

CAT: 0013-GTR19162068-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162068-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A synthetic antifungal agent that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase; used to treat ringworm, pityriasis versicolor, and fungal nail infections.Fungal Infection Approved (In Vitro) :Terbinafine has a primary fungicidal action in vitro against most fungal pathogens, including dermatophytes, and dimorphic and filamentous fungi. Terbinafine specifically inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation. The treated fungal cells rapidly accumulate tlic intermediate squalene and become deficient in the end-product of the pathway, ergosterol. (In Vivo) :Terbinafine is not only active after topical application but is very effective in experimental dermatophytoses following oral administration. In fungi infected guinea-pigs, the skin temperature dropps dramatically after the fourth treatment of terbinafine.
CAS Number
78628-80-5
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CC (C) (C) C#C/C=C/CN (C) CC1=CC=CC2=CC=CC=C21.Cl
Molecular Formula
C21H26ClN
Molecular Weight
327.8908
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Naphthalenemethanamine, N-[ (2E) -6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1)

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